DTPA Diethylenetriaminepentaacetic Acid
 

Product introduction

Product name: DTPA
Classification: Diethylenetriaminepentaacetic acid
CAS No.: 67-43-6
Other Names: Pentetic acid
MF: C14H23O10N3
Purity: ≥99.0%

Certificate of Analysis

Product description

    DTPA is a white crystal powder. The conjugate base of DTPA has a high affinity for metal cations. Thus, the penta-anion DTPA5− is potentially an octadentate ligand assuming that each nitrogen centre and each COO−-group counts as a centre for coordination. The formation constants for its complexes are about 100 greater than those for EDTA.

      As a chelating agent, DTPA wraps around a metal ion by forming up to eight bonds. Transition metals, however, usually form less than eight coordination bonds. So, after forming a complex with a metal, DTPA still has the ability to bind to other reagents, as is shown by its derivative pendetide. For example, in its complex with copper(II), DTPA binds in a hexadentate manner utilizing the three amine centres and three of the five carboxylates.

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