| Other Name :Rimegepant sulfate | Nurtec odt (TN) | DTXSID60160174 | D10663 | UNII-1383NM3Q0H | DTXCID9082665 | 1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo(4,5-b)pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohept | |
| Purity ≥99% | |
| Name:Rimegepant sulfate | |
| ANTAGONIST | |
| 1 |
| Rimegepant | |
| [(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate | |
| Rimegepant (BMS-927711) (CGRP) ,Ki 0.027 nM. | |||||||||||||
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CGRP
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CGRP
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Ki: 0.027 nM (CGRP receptor)[1] IC50: 0.14 nM (CGRP receptor)[1] |
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| Rimegepant(BMS-927711),CGRP,IC500.14±0.01 nM [1]. | |||||||||||||
| Rimegepant(BMS-927711),,CGRP[1].,Rimegepant(BMS-927711)(60,100300mg / kg)DBSAUC(0-24h)0.5-0.6.(DBS)Rimegepant[2]. | |||||||||||||
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DMSO:10 mg / mL(18.71 mM;) :10 mg / mL(18.71 mM;) :1.:90%PEG-300 10%:≥1mg / mL(1.87 mM); |
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