Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest

Model NO.
65928-58-7
EINECS
639-448-2
Appearance
Powder
Quality
Refined
Product Name
Dienogestrel
Grade Standard
Pharm Grade
Function
Healthcare
Shelf Life
2 Years
Certificate
GMP ISO USP Bp
Storage
Cool Dry Place
Transport Package
Dry and Cool
Specification
1kg/Bag, 25kg/Drum
Trademark
Gina
Origin
Shaanxi, China
Production Capacity
100000 Kilogram/ Month
Reference Price
$ 31.50 - 72.00
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Product Description

Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
What is Dienogest ?

Dienogest is a progestin, or a synthetic progestogen, of the group. It is available incombination with estradiol valerate (as Natazia, Qlaira) or ethinylestradiol (as Valette) for use as an oral contraceptive, and by itself (as Visanne, Dinagest) for the treatment of endometriosis in Europe, Australia, and Japan. Although available in combination with estrogen as a contraceptive in the United States, dienogest is not available in this country by itself. In addition to its progestogenic effects, dienogest has antiandrogenic activity, and as a result can improve androgenic symptoms such as acne.
 
Product Name Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
Appearance White powder
Molecular formula C20H25NO2
Molecular Weight 311.43
Keywords Dienogest Powder;Dienogest Dienogestrel;Dienogest CAS 65928-58-7
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location

 
Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest

Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
Endometriosis is a chronic, estrogen-dependent disease that affects approximately 10% of women of reproductive age, with a peak incidence in the age range of 25-30 years.1-3 Endometriosis is characterized by the formation of endometriotic lesions outside the uterus, including the ovaries and other pelvic structures. These lesions cause a chronic, inflammatory reaction, which can lead to the formation of scar tissue and adhesions.4 Women with endometriosis frequently experience symptoms of dysmenorrhea, premenstrual pain, dyspareunia, and chronic fatigue.5 Endometriosis can also interfere with functioning of the bowel or bladder, depending on the site where endometriotic lesions develop. Up to 50% of women with endometriosis experience infertility.6 However, the clinical presentations of endometriosis can vary widely, and many affected women are asymptomatic.7 No clear relationship exists between the extent of endometriotic lesions and a woman's symptoms.

Application of Dienogest 

(1). Dienogest has moderate affinity for the progesterone receptor in human uterus tissue, in vitro, about 10% that of progesterone.
(2). Inhibition of ovulation
The minimum effective dose of oral dienogest required to inhibit ovulation is 1 mg/day. The inhibition of ovulation by dienogest occurs mainly via peripheral action as opposed to central action on gonadotrophin secretion. Oral treatment of dienogest 2 mg/day in cyclical women reduced serum progesterone levels to anovulatory levels, however serum levels of lutenising hormone and follicle-stimulating hormone are not significantly altered. 

Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
Product Name Specification CAS No.
Medroxyprogesterone Acetate USP39/EP8.0 71-58-9
Altrenogest In-house standard 850-52-2
Progesterone USP39/EP8.0/BP2016 57-83-0
Estradiol USP39/EP8.0 50-28-2
Estradiol USP37 313-06-4
Estradiol Valerate USP39 979-32-8
Estradiol Benzoate USP38 50-50-0
Estrone USP39 53-16-7
Estriol USP41 50-27-1
Dienogest In-house standard 65928-58-7
Medrogestone In-house standard 977-79-7
Intermediates
Diosgenin In-house standard 512-04-9
16-Dehydropregnenolone acetate In-house standard 979-02-2
Megestrol Acetate USP39 595-33-5
Pregnenolone In-house standard 145-13-1
Pregnenolone acetate In-house standard 1778-02-5
17alpha-Hydroxyprogesterone In-house standard 604-09-1
Hydroxyprogesterone Acetate In-house standard 302-23-8
8DM(16alpha-methyl Epoxide) In-house standard 24916-90-3
Intermediate of Medrogestone In-house standard 902768-49-4
Steroid
Acid In-house standard 28416-82-2
Mometasone furoate USP38/EP7.0 83919-23-7
Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest
Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest Wholesale Medicine Grade Raw Materials Dienogest Powder CAS 65928-58-7 Dienogestrel /Dienogest

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