Factory Supply 1, 4-Dihydronicotinamide Riboside CAS 19132-12-8 Reliable Quality & Global Supply
Product Description
1,4-dihydronicotinamide is a key organic compound and the reduced form of nicotinamide, playing critical roles in biological redox reactions.
Basic Properties
Chemical Structure: It features a six-membered pyridine ring with an amide group (-CONH2) at the 3-position, and two hydrogen atoms added to the 1st and 4th carbon atoms of the ring, which distinguishes it from the oxidized nicotinamide.
Stability: It is relatively unstable and prone to oxidation in air, easily converting back to nicotinamide. For this reason, it is often stored under inert gas or in sealed, light-proof containers.
Biological Significance
Core Role in Redox Reactions: It serves as the active functional moiety of the reduced form of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH). In these coenzymes, 1,4-dihydronicotinamide donates hydrogen atoms (or electrons) to participate in various metabolic reactions in organisms.
Involvement in Metabolic Pathways: It is widely involved in carbohydrate, lipid, and amino acid metabolism. For example, it participates in the tricarboxylic acid cycle and oxidative phosphorylation, helping to generate adenosine triphosphate (ATP), the energy currency of cells.
Main Applications
Biochemical Research: It is used as a model compound to study the mechanism of redox reactions mediated by NADH/NADPH, and as a substrate in enzyme activity detection experiments.
Nutraceutical Fields: Derivatives of 1,4-dihydronicotinamide are explored for their potential in developing drugs targeting metabolic disorders or as nutritional supplements to support cellular energy metabolism.
| Product name | Reduced nicotinamide riboside(NRH) |
| Other name |
1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide;
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4H-pyridine-3-carboxamide;
1,4-dihydro-1beta-d-ribofuranosyl-3-pyridinecarboxamide; 1-(beta-D-ribofuranosyl)-1,4-dihydropyridine-3-carboxamide; |
| CAS No. | 19132-12-8 |
| Molecular formula | C11H16N2O5 |
| Molecular weight | 256.26 |
| Purity | 98% |
| Packing | 1kg/bag;25kg/drum |
| Application | dietary supplement raw materials |
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