| Product name | Dihydroberberine |
| CAS No | 4483-15-8 |
| Solubility | Soluble to 57.46 mg/l in water;Soluble in DMSO |
| Assay | 98% min |
| MOQ | 50g |
| Molrcular Formular |
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Dihydroberberine (DHB) is a bioactive form of berberine. When metabolizing berberine, our bodies form dihydroberberine. More specifically, enzymes such as cytochrome P450 reductases and other hepatic enzymes mainly convert the precursor substance, berberine, into dihydroberberine in the liver. Additionally, the microbes in the intestinal
gut
convert berberine to Dihydroberberine as well, proving that, at least in animals, the microbiome acts as an "organ" for Dihydroberberine production.
One of the biggest limitations of traditional Berberine HCl is poor absorption . Studies show that only a small fraction -as little as 1%-of oral berberine is absorbed into systemic circulation. Much of it is metabolized by gut bacteria and excreted.
Dihydroberberine, on the other hand, is far more efficient :
Up to 5x more bioavailable than Berberine HCl
Reaches peak plasma levels more quickly
Remains active longer in the bloodstream
Requires a lower dose to achieve the same effect
Dihydroberberine has been shown to:
Lower blood glucose levels
Reduce cholesterol and triglycerides
Support gut health
Modulate inflammation
Aid in weight control and fat metabolism