Product Name: Triethylamine hydrochloride
CAS Number: 554-68-7
Molecular Formula: C6H15N.HCl or C6H16ClN
Molecular Weight: 137.65
Appearance: White crystalline powder or colorless crystals, hygroscopic in air.
Solubility: Highly soluble in water (solubility ~ 245 g/L at 20°C), freely soluble in polar solvents such as ethanol and methanol, insoluble in nonpolar solvents like ether and benzene.
Melting Point: 254-256°C (decomposes upon heating).
pH: Aqueous solution is weakly acidic due to hydrolysis of the chloride ion.
Main Applications
Organic Synthesis:
Catalyst/Reagent:
Used as an acid-binding agent in condensation, acylation, and alkylation reactions to neutralize byproduct HCl.
Example: In peptide synthesis, it removes HCl generated during coupling reactions to maintain reaction pH.
Intermediate: Converted to triethylamine for use in pharmaceutical and agrochemical synthesis (e.g., in the production of antibiotics and herbicides).
Pharmaceuticals and Biotechnology:
pH Adjustment: In biochemical experiments, used to adjust buffer systems (e.g., in chromatography mobile phases).
Drug Formulation: As a salt form to improve the water solubility of basic drugs (though triethylamine itself has limited pharmaceutical use due to toxicity).
Electronics and Coatings:
Solvent Additive: In the production of coatings and electronic materials, regulates viscosity and improves film-forming properties.
Laboratory Reagent:
Commonly used in organic chemistry labs as a stable, easy-to-handle source of triethylamine (avoiding the volatility and odor of free-base triethylamine).
Safety and Handling
Hazards:
Health Risks:
Irritating to eyes, skin, and respiratory tract;
Ingestion may cause gastrointestinal irritation;
Triethylamine vapor (released upon decomposition) is toxic and has a strong odor.
Environmental Impact: May be harmful to aquatic life if released in large quantities; avoid direct discharge into water systems.
Protective Measures:
Wear gloves, safety goggles, and a lab coat; work in a fume hood to prevent inhalation of dust or decomposed vapors.
In case of skin/eye contact, rinse immediately with plenty of water; if inhaled, move to fresh air and seek medical attention.
Storage:
Store in a tightly sealed container in a cool, dry place, away from moisture and strong bases.
Keep separate from oxidizing agents and alkaline substances to avoid reactions.
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.