Basic Information
Product Name: 2-(2-Aminothiazol-4-yl)acetic Acid Hydrochloride
Molecular Formula: C5H6N2O2S.HCl
Molecular Weight: 208.64 g/mol (including hydrochloride)
CAS Number: 66659-20-9
Appearance: White to off-white crystalline powder.
Solubility: Highly soluble in water; soluble in polar organic solvents (e.g., methanol, ethanol).
Melting Point: Typically decomposes before melting (decomposition temperature > 200°C, specific value may vary with purity).
pH Behavior: As a hydrochloride salt, it dissociates in water to release H ions, forming an acidic solution.

Applications
Pharmaceutical Intermediate:
Critical precursor in the synthesis of β-lactam antibiotics (e.g., cephalosporins and penicillins), particularly for constructing the side chain of semi-synthetic antibiotics.
Used in the production of ceftazidime, cefotaxime, and other cephalosporin drugs.
Organic Synthesis:
Serve as a building block for heterocyclic compounds in medicinal chemistry and agrochemical research.

Safety and Handling
Hazards:
Irritating to eyes, skin, and respiratory tract; avoid direct contact or inhalation.
Non-flammable but may release toxic sulfur or nitrogen oxides when heated to decomposition.
Storage: Store in a sealed container at room temperature, protected from moisture and light.
Protective Measures: Use gloves, safety glasses, and a fume hood during handling.
Regulatory and Quality Standards
Compliance with pharmaceutical-grade standards (e.g., USP, EP, or JP) is common for its use in drug synthesis.
Purity requirements often exceed 98% (HPLC), with strict control of heavy metals and residual solvents.

Market Significance
Widely used in the pharmaceutical industry due to its role in antibiotic production, making it a key component in global antibiotic supply chains.
Synthetic methods are continuously optimized to improve yield and reduce environmental impact (e.g., using greener solvents or catalyst systems).
 

Packaging can be customized according to customer requirements.

Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.