Name: 3,3'-Diindolylmethane
English synonyms: 3,3'-Diindolylmethane (DIM)
CAS Number: 1968-05-4
Molecular formula: C17H14N2
Molecular weight: 246.31
EINECS number: 100-201-5
Melting point: 167°C
Boiling point: 230°C(Press:0.01Torr)
Density: 1.271±0.06g/cm3(Predicted)
Storage conditions: 2-8°C
Form: Off-whitepowder.
Acidity coefficient (pKa): 16.91±0.30 (Predicted)
 can be found in natural phytochemicals belonging to cruciferous plants, acid-catalyzed reaction product, indole-3-methanol; has the function of anti-tumor agent; this derivative, under relatively high concentration conditions, both It can directly accelerate the apoptosis of human cancer cells, and can also sensitize TRAIL to induce the apoptosis of human cancer cells; DIM induces a G1 cell loop inhibition, in human breast cancer MCF-7 cells, through mechanism, including expression; DIM is a strong A powerful inhibitor of mitochondrial H+-ATPase; as a new plant growth promoter, the functions of DIM and its derivatives have been used in eco-friendly system research

 

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